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The Citric Acid Cycle


Problems

Problem : What is the name of the enzyme that catalyzes the reaction that joins a molecule of acetyl-CoA and oxaloacetate?


Problem : From which position on citrate to which position is the –OH group transferred in the second step of the citric acid cycle by the enzyme acontinase?


Problem : What two types of reactions are catalyzed by the enzyme isocitrate dehydrogenase in the third reaction of the citric acid cycle?


Problem : In which of the first five steps of the citric acid cycle is NADH produced?


Problem : What citric acid cycle enzyme is responsible for catalyzing the reaction that produces GTP?


Problem : Fill in the blanks with the appropriate choice. FAD is the __________ (oxidized/reduced) form of flavin adenine dinucleotide while FADH is the __________ (oxidized/reduced) form.


Problem : What is the product when succinate is oxidized by the removal of two hydrogens by the enzyme succinate dehydrogenase?


Problem : Which molecule, NAD or FAD, would likely oxidize the following molecule?

Figure %: Oxidation of an alcohol to an aldehyde.


Problem : Name the enzyme that converts fumarate to L-malate.


Problem : Name the "final product" of the citric acid cycle. Why is this product not really the final product?