Mendelian
and Molecular Genetics
The word inheritance usually
brings to mind money or property left by a relative who has passed
away. But there’s another type of inheritance that is right under
our noses—actually, your nose is part of the inheritance. Every
living organism has characteristics or features that it passes on
to its offspring. These tendencies of heredity are
obvious: even a child knows cows give birth only to other cows,
and that children often look like their parents. But, in fact, the
specific biological mechanisms that allow parents to transmit their
features to their offspring were an enormous mystery until about
140 years ago. Scientists back then knew that parents somehow made
a tiny copy of themselves inside an egg or a sperm, but they had
no idea what these copies were or how they worked.
Then, in the 1860s, an Austrian monk named Gregor
Mendel started breeding peas in his garden. Where others
saw only plants, Mendel looked deeper and found the basic units
of heredity we now call genes. If you remember from
the last chapter, genes are the parts of a chromosome that are transcribed
to mRNA and are ultimately translated to the proteins essential
to cellular processes. Mendel had no knowledge of protein synthesis
and had never seen a chromosome, but his simple experiments with
peas and the laws he developed to describe the behavior of hereditary—now
termed classical genetics—have provided the foundation for the modern
field of molecular genetics, the study of heredity on the molecular
level.
For the SAT II Biology, you need a solid understanding
of the basic laws and patterns of both classical genetics and molecular
genetics. Questions on genetics can make up anywhere from 14 to
20 percent of the core of the SAT II Biology. In addition, the “M”
section of the Biology E/M test focuses on evolution in terms of
molecular biology, including genetics.