Organic Chemistry: Review of Organic 4

The rate law shows:

Which of the following is the best leaving group?

In the E2 reaction, which of the following donates into the C-LG antibond?

A S_N2 reaction will be fastest in which of the following solvents?

A S_N1 reaction proceeds with

In order for a E2 reaction to take place, which of the following must be present?

Choose the most stable olefin

If S_N2 reactions occurred through frontside attack, there would be

Predict the product

Which of reaction mechanism will dominated for this reaction?

The rate law of the above reaction is:

What is the overall order of this rate law?

The E2 mechanism is

Why will this molecule not undergo an E2 elimination?

A polar, aprotic solvent favors which mechanism most?

What is the rate-limiting step of the E1 mechanism?

Which of the following is a polar, aprotic solvent?

What is the predominant E2 product?

Which of the following is the best description of the E2 reaction?

S_N2 reactions generally proceed with

What is the major elimination product of this reaction?

What is the most reasonable reaction mechanism?

Can this molecule undergo an E2 reaction?

S_N2 reactions are favored by

Which one of the following bases is best suited for the E2 reaction?

Choose the most energetically stable E2 product.

An increase in a transition state's energy necessarily requires

What will be the absolute stereochemistry of the product?

After elimination, which of the following will form the most stable alkene?

How many β -hydrogens are there on this molecule?

How many of these β -hydrogens are antiperiplanar to the C-LG bond?

Predict the E2 elimination product.

Choose the most stable carbocation

Predict the most stable carbocation intermediate formed after LG leaves.

Predict the product

All other things being equal, a S_N1 reaction will be fastest in which solvent?

This molecule does not undergo S_N2 attack. Choose the best explanation.

Molecule A is formed through a S_N2 reaction. Which pair of reactants would give the highest yield of molecule A?

The activation energy of concerted reaction A is twice that of concerted reaction B. Which of the following must be true?

Why is this molecule not a good candidate for E1 ?

Which of the following is the best nucleophile?

Which of the following is the best leaving group?

Which of the following will promote the fastest E1 / S_N1 reaction?

Assuming no rotation about the C-C bond, which of the following pairs is antiperiplanar?

Choose the polar, protic solvent

Choose the most abundant E2 product

Predict the stereochemistry of the E2 product. (Hint: try rotating the C-C bond)

If the previous molecule is subjected to E1 conditions, what will be the stereochemistry of the most energetically stable product?

This molecule could be the product of only

X is thought to substitute for Br with a frontside attack mechanism. Predict the probably absolute stereochemistry of the product. Assume that X has the same CIP priority as Br.

Predict the major S_N2 product.