Problem : 
What is the name of the structure that forms during prophase and is responsible 
for aligning chromosomes in later mitotic phases?
During prophase a complex of microtubules organized around a centrosome forms 
the mitotic spindle which is responsible for organizing chromosomes for later 
separation.
 
Problem : 
What is the most visible physical characteristic of cells in prophase?
Cells in prophase are marked by very dark, condensed chromosomes.  This trait 
can be seen under a microscope.
 
Problem : 
What major event marks the beginning of prometaphase?
The breakdown of the nuclear envelope is the major event that starts 
prometaphase.
 
Problem : 
What is the name of the structure that forms on the centromere of a chromosome 
during late prophase and prometaphase?
A kinetochore.
 
Problem : 
What name is given to the microtubules that attach to chromosomes after the 
nuclear envelope has been destroyed in prometaphase?
Kinetochore microtubules.