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The Chemistry of the Primary RNA Transcript Splicing Reaction and Alternative Splicing
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Post-Transcriptional RNA Processing
Problems
Problem 3.1:
The splicing reaction results in the formation of two structures. Starting with
a structure composed of two exons (exon 1 and exon 2) that are separated by an
intron, what will be the composition (intron, exon 1, exon 2) or the two
splicing products?
[Solution]
Problem 3.2:
Describe the event that takes place during the first splicing step.
[Solution]
Problem 3.3:
What is the name of the looped structure that is formed after the first splicing
step?
[Solution]
Problem 3.4:
Describe the event that occurs in the second splicing step.
[Solution]
Problem 3.5:
What is the benefit of alternative splicing? Could there also be drawbacks to
alternative splicing?
[Solution]
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