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Middlesex is a novel by Jeffrey Eugenides that was published in 2002 and won the Pulitzer Prize for Fiction in 2003
. The novel follows the life of Cal Stephanides, a Greek-American intersex individual, as he grows up in Detroit and eventually comes to terms with their changing identity. Middlesex is a multigenerational family saga that explores themes of gender and sexuality, immigration and assimilation, and the nature of identity. It is also a historical fiction novel that touches on significant events and cultural shifts in the United States from the early 20th century to more recent times.Explore a character analysis of Cal/Calliope, plot summary, and important quotes.