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Middlesex is a novel by Jeffrey Eugenides that was published in 2002 and won the Pulitzer Prize for Fiction in 2003
. The novel follows the life of Cal Stephanides, a Greek-American intersex individual, as he grows up in Detroit and eventually comes to terms with their changing identity. Middlesex is a multigenerational family saga that explores themes of gender and sexuality, immigration and assimilation, and the nature of identity. It is also a historical fiction novel that touches on significant events and cultural shifts in the United States from the early 20th century to more recent times. In 2024, Middlesex was named one of the 100 Best Books of the 21st Century by the New York Times.Read the full book summary, an in-depth character analysis of Cal/Calliope, and explanations of important quotes from Middlesex.