On May 6, 1856, Sigismund Schlomo Freud was born in the small Moravian town of Freiberg. His parents were Jakob and Amalie Freud. Over the next six years Amalie gave birth to six more children. Sigmund was always the favorite child. Jakob's textile business failed, and in 1860, the family moved to Vienna, spending almost a year in Leipzig on the way. In Vienna, Freud was a studious and serious child. He was schooled at home, first by his mother and then by his father, and then he joined the Sperl Gymnasium, where he was at the top of his class.

In 1873, Freud graduated from the Sperl Gymnasium at the early age of seventeen and started medical training at the University of Vienna. It took him eight years to receive his medical degree, in part because he was distracted by scientific research. This was especially true in the later years of his medical studies (1877–1881), when was working in the laboratory of his mentor, Ernst Brücke, on the anatomy of the brain.

1881 was a momentous year for Freud: he met Martha Bernays and became engaged to her–secretly, at first–and he finally received his medical degree. In 1882, he left Brücke's lab and took a position at the Vienna General Hospital, motivated in part by his desire to make enough money to be able to marry Martha. Over the next five years he moved from department to department at the hospital, passing through surgery and dermatology before coming to rest at Theodor Meynert's department of psychiatry. In the winter of 1885–1886, Freud went to Paris to study under Jean-Martin Charcot at the Salpêtrière. He was finally married to Martha Bernays in the summer of 1886. They first married in a civil ceremony, but when they discovered that Austria (unlike Germany) would not officially recognize a nonreligious marriage, they married in a Jewish one.

Over the next ten years, from 1886–1896, Freud continued to develop his private practice. By the beginning of the 1890s, his relationship with Josef Breuer, another Jewish neurologist, had flourished. The two men had collaborated on the publication of a series of case studies on their patients called Studies on Hysteria. This contained one case study by Breuer and four by Freud. The case study by Breuer, on the patient "Anna O.", is known as the first psychoanalytic case study. In it, Breuer discusses the "cathartic method" he used to cure Anna O.'s symptoms by discovering, with her help, the earlier, unconscious traumas that were associated with her symptoms. Although Freud was enthusiastic about the new method, his emphasis on the exclusively sexual causes of hysteria made his theories unpopular, not only with his superiors at the University, but also with Breuer.

From 1896–1901, in a period of isolation from his colleagues, Freud developed the basics of psychoanalytic theory out of the raw material of his patients, his conversations with Breuer, and his correspondence with a new friend, the Berlin nose and throat doctor Wilhelm Fliess. In 1899, Freud's The Interpretation of Dreams, the first fully fleshed-out psychoanalytic work, was published. Freud was deeply disappointed by its lackluster reception, but he continued writing. His The Psychopathology of Everyday Life was published in 1901, and his Three Essays on the Theory of Sexuality was published in 1905.

In the 1900s, Freud finally emerged from the isolation that had characterized his professional life in the 1890s. He began to have weekly meetings at his house to discuss psychoanalytic theory. The group that met at his house was called the "Wednesday Psychological Society," and eventually it grew into the Vienna Psycho-Analytic Society. By 1904, Freud had begun to hear of other neurologists and psychiatrists using his techniques. He was particularly excited to hear that the well-respected Swiss psychiatrist Eugen Bleuler and one of Bleuler's staff members, Carl G. Jung, had taken an interest. Toward the end of the decade, psychoanalysis became a truly international affair: the International Psychoanalytic Association was founded with the help of supporters from Germany, Austria (Alfred Adler and Wilhelm Stekel), Switzerland, Hungary (Sandor Ferenczi), and England (Ernest Jones). In the years before the First World War, psychoanalysis experienced its first growing pains: first Jung, then Adler and Stekel, left the organization after bitter disagreements with Freud. In response to these defections, Jones and Freud created a secret "Committee" to protect psychoanalysis. The committee consisted of Jones, Ferenczi, Karl Abraham, Otto Rank, and Hanns Sachs.

During World War I, Freud continued to write and lecture, but patients were few and international communications were impossible. When the war ended, however, the International Psychoanalytic Association resumed its meetings in an atmosphere much more conducive to psychoanalysis than that before the war. Unfortunately, the post-war years were extremely difficult in Vienna: inflation was rampant, supplies were few, and patients were rare. Freud's reputation, however, was growing, and in 1919 he was made a full professor at the University of Vienna.

Freud's work from 1919 to the end of his life in 1938 became increasingly speculative. He became concerned with applying psychoanalysis to questions of civilization and society, an approach that he had first tried in his 1913 Totem and Taboo. In 1920, he published Beyond the Pleasure Principle, which suggested that human existence is a struggle between Eros, or the sex drive, and an instinct toward death.

In 1923, Freud was diagnosed with mouth cancer, a consequence of his life-long habit of cigar smoking. His illness would trouble him until his death in 1938, demanding in the meantime thirty-three separate operations that caused him pain and made it difficult for him to speak and eat. The 1920s were a complicated decade for Freud. He was undeniably successful, even famous, but his own health, several deaths in his family, and the disintegration of the Committee made his success bittersweet.

In the 1930s, Freud continued to treat patients and to write. He published one of his most frequently read books, Civilization and Its Discontents, in 1930. The rise of Nazism in Germany, however, and its echoes in Austria, made life in Vienna increasingly untenable. Freud stayed as long as he could, but when the Nazis invaded Austria in 1938 and raided his house, he fled to England with most of his family. He died there on September 23, 1939.

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