Of Mice and Men, 1939
Director: Lewis Milestone
Notable Cast: Burgess Meredith, Betty Field

This adaptation added several new scenes in order to expand the role of Curley’s wife.

Of Mice and Men, 1992
Director: Gary Sinise
Notable Cast: John Malkovich, Gary Sinise

Apart from brief scenes imagining George’s life after Lennie’s death, this adaptation is largely faithful to the novella.