Francis Nurse is a well-respected man within the community. He is often called upon to resolve disputes and has emerged as "an unofficial judge" for the people of Salem. He is someone "for whom both sides of the argument had to have respect." 

Despite his prominent standing in the community, many townspeople have harbored resentment towards Francis, contributing to one of the play’s most notable thematic ideas: holding grudges. His rise in social status and accumulation of land and wealth have sparked some jealousy and contempt in the town. It is suspected that these personal grudges have contributed to "the systematic campaign" against his wife, Rebecca. The crusade launched against Francis's wife illustrates the wider inclination to weaponize accusations as a means of satisfying personal grudges and feuds. 

Francis's strong moral character perseveres throughout the play. He remains rational and sensible throughout the trial, in direct contrast to the hysteria that has seized control of Salem. He vehemently stands by his wife after she is accused and defends her honor and goodness. His character directly contrasts Reverend Parris, who is more concerned with protecting his reputation than defending the honor of his accused daughter and niece. Francis also grows indignant when it is suggested that he unknowingly brought many people to harm by presenting the list of 91 names that can vouch for the characters of the accused. Francis clearly has a strong personal sense of justice but Hale urges Francis to trust the justice of the court, the irony being that there is no real justice in the courts of Salem. Trials are skewed and driven by false and vindictive accusations aimed to increase personal gain and protect social status.